Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

Martine Piccart, Marion Procter, Brian Leyland‐Jones et al. · New England Journal of Medicine · 2005 · 5.1K citations · Full text

Medicine, Oncology, Pharmacology +16

Trastuzumab-Induced Hepatotoxicity: A Case Report

D. Vucicevic, Elizabeth J. Carey, Nina J. Karlin · Breast Care · 2013 · 4.4K citations · Full text

Medicine, Oncology, Pharmacotherapy +17

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

Balázs Győrffy, András Lánczky, Aron C. Eklund et al. · Breast Cancer Research and Treatment · 2009 · 4.3K citations

Medicine, Bioinformatics, Oncology +15

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

William J. Muller, Eric Sinn, Paul K. Pattengale et al. · Cell · 1988 · 1.2K citations

Medicine, Cancer Biology, Oncology +14