Concepedia

Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo

Naito Kurio, Tsuyoshi Shimo, Takuya Fukazawa, Munenori Takaoka, Tatsuo Okui, Nur Mohammad Monsur Hassan, Tatsuki Honami, Shinji Hatakeyama, Masahiko Ikeda, Yoshio Naomoto,

Experimental Cell Research · 2011 · 55 citations · 21 references

Concepts

MedicineCancer BiologyOncologyBreast OncologyCancer PharmacologyMolecular OncologyCancer Cell SignalingMetastatic Breast CancerPharmacodynamics Of Anticancer AgentsTargeted Cancer TherapyTargeted TherapyTyrosine Kinase InhibitorsCancer Cell Proliferation InhibitionMek InhibitionMek InhibitorsMetastatic Breast Cancer Treatment

References

21

Mechanisms of Bone Metastasis

G. David Roodman · New England Journal of Medicine · 2004 · 2.7K citations

Medicine, Oncology, Bone Metabolism +12

Breast Tumor Cell Lines From Pleural Effusions2

Relda Cailleau, Russell K. Young, Matilde Olivé et al. · JNCI Journal of the National Cancer Institute · 1974 · 1K citations · Full text

Veterinary Medicine, Cell Biology, Oncology +13

Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice.

Akira Sasaki, Brendan F. Boyce, Beryl Story et al. · PubMed · 1995 · 422 citations

Medicine, Oncology, Pharmacology +17

Activation of ZAP‐70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

Andrew C. Chan, Mark Dalton, Richard C. Johnson et al. · The EMBO Journal · 1995 · 357 citations · Full text

Life Sciences, Immunology, Molecular Biology +11

Peter Traxler, Peter R. Allegrini, Ralf Brandt et al. · Cancer Research · 2004 · 318 citations

Medicine, Oncology, Pharmacology +17