Quantification of metabolic limitations during recombinant protein production in Escherichia coli

Metabolic load and heterologous gene expression

Bernard R. Glick · Biotechnology Advances · 1995 · 677 citations

Life Sciences, Biotechnology, Molecular Biology +14

The Soluble and Membrane-bound Transhydrogenases UdhA and PntAB Have Divergent Functions in NADPH Metabolism of Escherichia coli

Uwe Sauer, Fabrizio Canonaco, Sylvia Heri et al. · Journal of Biological Chemistry · 2004 · 614 citations · Full text

Life Sciences, Microbiology, Physiology +13

Plasmid‐encoded protein: The principal factor in the “metabolic burden” associated with recombinant bacteria

William E. Bentley, N. Mirjalili, Dana C. Andersen et al. · Biotechnology and Bioengineering · 1990 · 538 citations

Life Sciences, Genetics, Microbiology +16

The Glycolytic Flux in <i>Escherichia coli</i> Is Controlled by the Demand for ATP

Brian J. Koebmann, Hans V. Westerhoff, Jacky L. Snoep et al. · Journal of Bacteriology · 2002 · 364 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Network Identification and Flux Quantification in the Central Metabolism of<i>Saccharomyces cerevisiae</i>under Different Conditions of Glucose Repression

Andreas Gombert, Margarida Moreira dos Santos, Bjarke Bak Christensen et al. · Journal of Bacteriology · 2001 · 344 citations · Full text

Life Sciences, Biochemistry, Microbiology +17