Concepedia

Sterile protection of monkeys against malaria after administration of interleukin-12

Stephen L. Hoffman, James M. Crutcher, S.K. Puri, Aftab A. Ansari, François Villinger, E D Franke, Priya Singh, Fred D. Finkelman, Maurice K. Gately, G. P. Dutta,

Nature Medicine · 1997 · 141 citations · 21 references

DOI

Concepts

References

21

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

Annalisa D’Andrea, Miguel Aste-Amézaga, Nicholas M. Valiante et al. · The Journal of Experimental Medicine · 1993 · 1.4K citations · Full text

, , +12

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

Giorgio Trinchieri · Blood · 1994 · 1.1K citations · Full text

, , +17

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.

Maurice K. Gately, Ueli Gubler, A S Stern et al. · The Journal of Immunology · 1995 · 407 citations

, , +16

IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism

Mary M. Stevenson, M. F. Tam, S F Wolf et al. · The Journal of Immunology · 1995 · 313 citations · Full text

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Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection.

Suzanne C. Morris, Kathleen B. Madden, Jeffrey J. Adamovicz et al. · The Journal of Immunology · 1994 · 286 citations · Full text

, , +16