The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

Chand Khanna, Xiaolin Wan, Seuli Bose et al. · Nature Medicine · 2004 · 718 citations

Life Sciences, Cancer Biology, Cell Biology +12

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

Ping Zhu, Elke Martin, Jörg Mengwasser et al. · Cancer Cell · 2004 · 535 citations · Full text

Medicine, Molecular Biology, Oncology +11

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

Wilko Weichert, A.-E. Roske, Volker Gekeler et al. · British Journal of Cancer · 2008 · 479 citations · Full text

Medicine, Molecular Biology, Oncology +17

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek et al. · PubMed · 2003 · 464 citations

Medicine, Oncology, Pharmacology +15

Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis

Wilko Weichert, A.-E. Roske, Volker Gekeler et al. · The Lancet Oncology · 2008 · 362 citations

Medicine, Molecular Biology, Oncology +16