Journal of the Chemical Society Chemical Communications · 1986 · 37 citations · 0 references
Natural SciencesBiochemistryChemistryBiocatalysisCatalysisEnzymologyBiocatalytic StereoselectivityCatalytic MechanismsEnzymatic CatalysisEnantioselective BiocatalysisEnantioselective CatalysisEnantioselective SynthesisEnantioselectivityEnantioselectivity ScreeningEsterase-mediated Hydrolysis
Pig liver esterase-catalysed hydrolyses of variously substituted racemic allenic esters proceed with predictable enantiomeric selectivity, with the highest (93%) enantiomeric excess values being observed for the most highly substituted substrates.