Concepedia

ANCA patients have T cells responsive to complementary PR-3 antigen

Jiajin Yang, David J. Bautz, Susan L. Hogan, Hyunsook Chin, Roland Tisch, John L. Schmitz, Barrak M. Pressler, J. Charles Jennette, Ronald J. Falk, Gloria A. Preston

Kidney International · 2008 · 52 citations · 42 references

Open access

Concepts

Life SciencesImmunologyAdaptive ImmunityAutoimmunityClinical ImmunologyAntigen RecognitionAutoantigensCell-mediated ImmunityT Cell ActivationT Cell BiologyT Cell Receptor SignalingAntigen-specific Immune ResponseAntigen-specific T Cell ResponsesT Cell-mediated Immune ResponseT-cell EpitopesT-cell Mediated Immune ResponseT-cell Mediated ImmunityT-cell Mediated Responses

References

42

New allele frequency database: http://www.allelefrequencies.net

Derek Middleton, L. Menchaca, H. Rood et al. · Tissue Antigens · 2003 · 387 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Autoimmunity is triggered by cPR-3(105–201), a protein complementary to human autoantigen proteinase-3

William F. Pendergraft, Gloria A. Preston, Ruchir Shah et al. · Nature Medicine · 2003 · 376 citations

Life Sciences, Immunology, Molecular Biology +14

Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells.

Amy E. Lovett‐Racke, John L. Trotter, Jörg Lauber et al. · Journal of Clinical Investigation · 1998 · 264 citations · Full text

Life Sciences, Immunology, Neurology +16

MHC class II—Restricted presentation of intracellular antigen

Bjarne Bogen · Cell · 1991 · 256 citations

Life Sciences, Cell Biology, Immunology +12

B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells.

Bjarne Bogen · Proceedings of the National Academy of Sciences · 1989 · 222 citations · Full text

Life Sciences, Cell Biology, Immunology +15