Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Medicine, Molecular Genetics, Oncology +16

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +11

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

Danny Liaw, Jing Li, Patricia L. M. Dahia et al. · Nature Genetics · 1997 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +16

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

Medicine, Genetics, Molecular Biology +17