Concepedia

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

Pasha Sarraf, Elisabetta Mueller, Wendy M. Smith, Harold M. Wright, Jennifer B. Kum, Lauri A. Aaltonen, Albert de la Chapelle, Bruce M. Spiegelman, Charis Eng

Molecular Cell · 1999 · 509 citations · 22 references

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22

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein et al. · PubMed · 1994 · 3.5K citations

, , +16

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

Danny Liaw, Jing Li, Patricia L. M. Dahia et al. · Nature Genetics · 1997 · 2.1K citations

, , +16

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson et al. · Cell · 1995 · 2K citations · Full text

, , +16

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Robert T. Nolte, G. Bruce Wisely, Stefan Westin et al. · Nature · 1998 · 1.9K citations

, , +12