Relationship among activation of the Na+/H+ antiporter, ornithine decarboxylase induction, and DNA synthesis

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

Wouter H. Moolenaar, Roger Y. Tsien, Paul T. van der Saag et al. · Nature · 1983 · 716 citations

Life Sciences, Biochemistry, Cell Biology +12

Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport.

Gilles L’Allemain, S Paris, Jacques Pouysségur · Journal of Biological Chemistry · 1984 · 354 citations · Full text

Life Sciences, Cell Biology, Physiology +11

Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

Gilles L’Allemain, A Franchi, Edward J. Cragoe et al. · Journal of Biological Chemistry · 1984 · 304 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.

Wouter H. Moolenaar, Yosef Yarden, Siegfried W. de Laat et al. · Journal of Biological Chemistry · 1982 · 219 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.

Jeffrey M. Besterman, W. Stratford May, Harry LeVine et al. · Journal of Biological Chemistry · 1985 · 203 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +7