Arg16gly Polymorphism of the beta2-Adrenoceptor Gene (ADRBeta2) as a Susceptibility Factor for Nasal Polyposis

Abstract

Although results of this study are preliminary because of the small size of the sample, the arg16 allele seems to be associated with an increased risk of sinonasal polyposis suggesting ADRB2 as a susceptibility gene. This finding, if confirmed, would have a clinical value in helping to assess the genetic risk for sinonasal polyposis thus opening new perspectives for the study of molecular factors underlying the development of nasal polyps.