Synthesis of thymidine dimer derivatives containing an amide linkage and their incorporation into oligodeoxyribonucleotides

An all atom force field for simulations of proteins and nucleic acids

Scott J. Weiner, Peter A. Kollman, Dzung T. Nguyen et al. · Journal of Computational Chemistry · 1986 · 3.4K citations

Natural Sciences, Biochemistry, Chemistry +17

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Serge L. Beaucage, Marvin H. Caruthers · Tetrahedron Letters · 1981 · 2K citations

Pharmacy, Biochemistry, Molecular Biology +7

New coupling reagents in peptide chemistry

Reinhard Knorr, Arnold Trzeciak, Willi Bannwarth et al. · Tetrahedron Letters · 1989 · 986 citations

Natural Sciences, Biochemistry, Chemistry +8

Polymer support oligonucleotide synthesis XVIII^1.2): use of<i>β</i>-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

N. D. SINHA, J. Biernat, J. F. A. McManus et al. · Nucleic Acids Research · 1984 · 848 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

Glenn D. Hoke, Kenneth Draper, Susan M. Freier et al. · Nucleic Acids Research · 1991 · 248 citations · Full text

Medicine, Infectious Diseases, Pharmacology +13