Plasmid DNA for Human Gene Therapy and DNA Vaccines Production and Quality Assurance

Direct Gene Transfer into Mouse Muscle in Vivo

Jon A. Wolff, Robert W. Malone, Phillip Williams et al. · Science · 1990 · 4.2K citations

Life Sciences, Genetics, Molecular Biology +16

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

Natasha J. Caplen, Eric W.F.W. Alton, Peter G. Mddleton et al. · Nature Medicine · 1995 · 707 citations

Pharmacy, Genetics, Molecular Biology +14

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

Marie‐Laure Michel, Heather L. Davis, Martin Schleef et al. · Proceedings of the National Academy of Sciences · 1995 · 263 citations

Life Sciences, Immunology, Infectious Diseases +17

Arterial Gene Therapy for Therapeutic Angiogenesis in Patients With Peripheral Artery Disease

Jeffrey M. Isner, Kenneth Walsh, James F. Symes et al. · Circulation · 1995 · 213 citations

Medicine, Biomedical Engineering, Surgery +16

Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen

Heather L. Davis, Marie‐Louise Michel, M Mancini et al. · Vaccine · 1994 · 174 citations

Life Sciences, Biotechnology, Molecular Biology +17