Matching cellular dimensions with molecular sizes

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

R. Eric Davis, Vu N. Ngo, Georg Lenz et al. · Nature · 2010 · 1.6K citations · Full text

Medicine, Hematology, Oncology +14

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76

Tadashi Yokosuka, Kumiko Sakata-Sogawa, Wakana Kobayashi et al. · Nature Immunology · 2005 · 694 citations

Life Sciences, Immunology, Molecular Biology +14

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

Björn F. Lillemeier, Manuel Mörtelmaier, Martin B. Forstner et al. · Nature Immunology · 2009 · 637 citations

Life Sciences, Immunology, Molecular Biology +13

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

Gabriele Campi, Rajat Varma, Michael L. Dustin · The Journal of Experimental Medicine · 2005 · 627 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

Marcus Dühren-von Minden, Rudolf Übelhart, Dunja Schneider et al. · Nature · 2012 · 500 citations

Life Sciences, Cell Biology, Immunology +12