Berberine down-regulates the Th1/Th2 cytokine gene expression ratio in mouse primary splenocytes in the absence or presence of lipopolysaccharide in a preventive manner

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

Functional Genomics, Engineering, Medicine +12

Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells

Kazunori Fukuda, Yuko Hibiya, Michihiro Mutoh et al. · Journal of Ethnopharmacology · 1999 · 269 citations

Chemoprevention Strategy, Oncogenic Agent, Medicine +7

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

Guoliang Cui, Xia Qin, Yuebo Zhang et al. · Journal of Biological Chemistry · 2009 · 198 citations · Full text

Immunology, Immune Regulation, P38 Mapk +18

Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway

Jeevitha B. Patil, Jinhee Kim, G.K. Jayaprakasha · European Journal of Pharmacology · 2010 · 188 citations

Berberine Induces Apoptosis, Mitochondrial Function, Medicine +11

Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability

Chris Cheadle, Jinshui Fan, Yoon S. Cho‐Chung et al. · BMC Genomics · 2005 · 186 citations · Full text