Cellular Inhibitor of Apoptosis Protein cIAP2 Protects against Pulmonary Tissue Necrosis during Influenza Virus Infection to Promote Host Survival

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

Life Sciences, Cell Biology, Molecular Biology +7

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

Medicine, Medicinal Chemistry, Pharmacology +17

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

Cun-Yu Wang, Marty W. Mayo, Robert G. Korneluk et al. · Science · 1998 · 2.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

Life Sciences, Cell Biology, Molecular Biology +10