Differential effects of mutant SOD1 on protein structure of skeletal muscle and spinal cord of familial amyotrophic lateral sclerosis: Role of chaperone network

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

Life Sciences, Genetics, Neuroscience +14

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations

Life Sciences, Genetics, Neuroscience +17

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

Lindsey R. Fischer, Deborah G. Culver, Philip Tennant et al. · Experimental Neurology · 2004 · 1.3K citations

Life Sciences, Neurology, Neuroscience +11

Early and Selective Loss of Neuromuscular Synapse Subtypes with Low Sprouting Competence in Motoneuron Diseases

Dunja Frey, Corinna Schneider, Lan Xu et al. · Journal of Neuroscience · 2000 · 685 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

Gabriella Dobrowolny, Michela Aucello, Emanuele Rizzuto et al. · Cell Metabolism · 2008 · 495 citations · Full text

Medicine, Cell Biology, Molecular Genetics +8