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Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid

Walker H. Busby, Sue A. Yocum, Michael A. Rowland, Debra Kellner, S. Lazerwith, Francis M. Sverdrup, M. Yates, M. Radabaugh, David R. Clemmons

Osteoarthritis and Cartilage · 2008 · 16 citations · 49 references

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49

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

Klara Sjögren, Jun‐Li Liu, K. Blad et al. · Proceedings of the National Academy of Sciences · 1999 · 954 citations

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Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I.

John I. Jones, A Gockerman, W H Busby et al. · The Journal of Cell Biology · 1993 · 544 citations · Full text

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Insulin-like growth factor-I enhances cell-based repair of articular cartilage

Lisa A. Fortier, Hassan Mohammed, G. Lust et al. · Journal of Bone and Joint Surgery - British Volume · 2002 · 332 citations · Full text

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ADAM 12-S Cleaves IGFBP-3 and IGFBP-5 and Is Inhibited by TIMP-3

Frosty Loechel, Jay W. Fox, Gillian Murphy et al. · Biochemical and Biophysical Research Communications · 2000 · 317 citations

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Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin.

Nicole Schlechter, Sharon M. Russell, Eugenio Spencer et al. · Proceedings of the National Academy of Sciences · 1986 · 310 citations

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