Concepedia

Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury

Roya Tehranian, Marie E. Rose, Vincent Vagni, Raymond P. Griffith, Shasha Wu, Sara Maits, Xiaopeng Zhang, Robert S. B. Clark, C. Edward Dixon, Patrick M. Kochanek,

Brain Research · 2006 · 25 citations · 34 references

DOI

Concepts

References

34

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

Joshua B. Bederson, L H Pitts, Masahiko Tsuji et al. · Stroke · 1986 · 2.7K citations

, , +16

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x <sub>L</sub> , but not Bcl-2, until displaced by BH3-only proteins

Simon N. Willis, Grant Dewson, Andrew H. Wei et al. · Genes & Development · 2005 · 1.2K citations · Full text

, , +17

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

Jean‐Claude Martinou, Michel Dubois‐Dauphin, Julie K. Staple et al. · Neuron · 1994 · 1.1K citations

, , +16

14-3-3 Proteins and Survival Kinases Cooperate to Inactivate BAD by BH3 Domain Phosphorylation

Sandeep Robert Datta, Alex Katsov, Linda Hu et al. · Molecular Cell · 2000 · 644 citations

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