Nature Structural & Molecular Biology · 2011 · 574 citations · 44 references
Molecular BiologyStructural BasisGene EditingGenome EditingOff-target EffectMedicineCrisprStructural Biology
44
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.2K citations
Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
Stan J. J. Brouns, Matthijs M. Jore, Magnus Lundgren et al. · Science · 2008 · 2.6K citations · Full text
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion et al. · Nature · 2010 · 2.3K citations