Concepedia

Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease

John P. Miller, Jennifer Holcomb, Ismael Al‐Ramahi, María de Haro, Juliette Gafni, Ningzhe Zhang, Eugene S. Kim, Mario Sanhueza, Cameron Torcassi, Seung Kwak,

Neuron · 2010 · 177 citations · 55 references

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55

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

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Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 649 citations · Full text

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Furin-dependent intracellular activation of the human stromelysin-3 zymogen

Duanqing Pei, Stephen J. Weiss · Nature · 1995 · 622 citations

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Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells

Flavia Trettel · Human Molecular Genetics · 2000 · 620 citations · Full text

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Role for Matrix Metalloproteinase 9 after Focal Cerebral Ischemia: Effects of Gene Knockout and Enzyme Inhibition with BB-94

Minoru Asahi, Kazuko Asahi, Jae‐Chang Jung et al. · Journal of Cerebral Blood Flow & Metabolism · 2000 · 604 citations · Full text

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