Inhibition of the mevalonate pathway potentiates the effects of lenalidomide in myeloma

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.7K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

Faith E. Davies, Noopur Raje, Teru Hideshima et al. · Blood · 2001 · 905 citations

Medicine, Immunology, Oncology +12

Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy

Teru Hideshima, Dharminder Chauhan, Yoshihito Shima et al. · Blood · 2000 · 859 citations

Medicine, Oncology, Pharmacology +16

Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma

Paul G. Richardson, Robert Schlossman, Edie Weller et al. · Blood · 2002 · 804 citations · Full text

Medicine, Immunology, Pharmacology +12