A tutorial on hidden Markov models and selected applications in speech recognition

L. R. Rabiner

Proceedings of the IEEE

EngineeringMachine LearningHidden StatesDiscrete Markov ChainsSpeech Recognition +17

A New Statistical Method for Haplotype Reconstruction from Population Data

Matthew Stephens, Nicholas Smith, Peter Donnelly

The American Journal of Human Genetics

Genetic AnalysisHaplotype ReconstructionHaplotype DeterminationGenotype-phenotype AssociationMolecular Ecology +9

A second generation human haplotype map of over 3.1 million SNPs

Liuda Ziaugra, Chibuzor Nkwodimmah, Missy Dixon, +4

Nature

Haplotype DeterminationGenotype-phenotype AssociationMedicineGeneticsHuman Polymorphism +5

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

Bryan Howie, Peter Donnelly, Jonathan Marchini

PLoS Genetics

Genotype Imputation MethodsGeneticsLinkage AnalysisGenomicsGenome-wide Association Studies +17

Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering

Sharon R. Browning, Brian L. Browning

The American Journal of Human Genetics

Genome-wide Association StudyGenetic AnalysisLocalized Haplotype ClusteringHaplotype DeterminationGenotype-phenotype Association +12

A new multipoint method for genome-wide association studies by imputation of genotypes

Jonathan Marchini, Bryan Howie, Simon Myers, +2

Nature Genetics

Genome-wide Association StudyGenetic AnalysisHaplotype DeterminationGenotype-phenotype AssociationNew Multipoint Method +11

Genome-wide detection and characterization of positive selection in human populations

Pardis C. Sabeti, Patrick Varilly, Ben Fry, +9

Nature

Genetic AnalysisGenome StudyMedicineGeneticsEvolutionary Biology +8

A Fast and Flexible Statistical Model for Large-Scale Population Genotype Data: Applications to Inferring Missing Genotypes and Haplotypic Phase

Paul Scheet, Matthew Stephens

The American Journal of Human Genetics

Haplotype DeterminationLinkage DisequilibriumGenotype-phenotype AssociationFlexible Statistical ModelMedicine +9

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Yun Li, Cristen J. Willer, Jun Ding, +2

Genetic Epidemiology

A Fine-Scale Map of Recombination Rates and Hotspots Across the Human Genome

Simon Myers, Leonardo Bottolo, Colin Freeman, +2

Science

GeneticsGenomicsMolecular EcologyHotspot ActivityComputational Genomics +16