Concepedia

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

Ji Won Um, A Kaufman, Mikhail A. Kostylev, Jacqueline K. Heiss, Massimiliano Stagi, Hideyuki Takahashi, Meghan E. Kerrisk, Alexander O. Vortmeyer, Anthony J. Koleske, Erik C. Gunther,

Neuron · 2013 · 563 citations · 55 references

DOIFull text

Open access

Concepts

References

55

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

, , +12

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan Mehta et al. · Nature Medicine · 2008 · 3.7K citations · Full text

, , +14

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

, , +16

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

Thorlákur Jónsson, Jasvinder K. Atwal, Stacy Steinberg et al. · Nature · 2012 · 1.7K citations

, , +16

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

Juha Laurén, David A. Gimbel, Haakon B. Nygaard et al. · Nature · 2009 · 1.5K citations · Full text

, , +16