Hideyuki Takahashi

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

Ji Won Um, A Kaufman, Mikhail A. Kostylev et al. · Neuron · 2013 · 553 citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +12

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

Daniel Franjic, Mario Škarica, Shaojie Ma et al. · Neuron · 2021 · 290 citations · Full text

Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice

Zoe A. Klein, Hideyuki Takahashi, Mengxiao Ma et al. · Neuron · 2017 · 169 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Dementia +14

Liquid and Hydrogel Phases of PrPC Linked to Conformation Shifts and Triggered by Alzheimer’s Amyloid-β Oligomers

Mikhail A. Kostylev, Marcus D. Tuttle, Suho Lee et al. · Molecular Cell · 2018 · 115 citations · Full text

Alzheimer's Disease, Protein Assembly, Protein Folding +10

Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q

Joshua Spurrier, LaShae Nicholson, Xiaotian T. Fang et al. · Science Translational Medicine · 2022 · 102 citations · Full text