Bilberry (<i>Vaccinium myrtillus</i>) Anthocyanins Modulate Heme Oxygenase-1 and Glutathione<i>S</i>-Transferase-pi Expression in ARPE-19 Cells

Abstract

Anthocyanins and other phenolics from bilberry upregulate the oxidative stress defense enzymes HO-1 and GST-pi in RPE, suggesting that they stimulate signal transduction pathways influencing genes controlled by the antioxidant response element.