Concepedia

The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK

H. Schüller, L. Zhang, Diann L. Weddle, André Castonguay, Kindra Walker, Michael Miller

Journal of Cancer Research and Clinical Oncology · 2002 · 85 citations · 26 references

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References

26

Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer.

Olga Tucker, Andrew J. Dannenberg, Eun Kyung Yang et al. · PubMed · 1999 · 694 citations

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Arachidonic Acid in Platelet Microparticles Up-regulates Cyclooxygenase-2-dependent Prostaglandin Formation via a Protein Kinase C/Mitogen-activated Protein Kinase-dependent Pathway

Órla P. Barry, Marcelo G. Kazanietz, Domenico Praticò et al. · Journal of Biological Chemistry · 1999 · 236 citations · Full text

, , +16

Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells.

Gadiparthi N. Rao, A. Baas, Wayne C. Glasgow et al. · Journal of Biological Chemistry · 1994 · 230 citations · Full text

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Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines

Steven A. Belinsky · Lung Cancer · 1990 · 209 citations

, , +15

Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.

Sung Hyeok Hong, Ingalill Avis, Michele D. Vos et al. · PubMed · 1999 · 148 citations

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