André Castonguay

Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398.

Nathalie Rioux, André Castonguay · PubMed · 1998 · 203 citations

Chemoprevention Strategy, Lung Inflammation, Oxidative Stress +17

Comparative carcinogenicity in A/J mice and metabolism by cultured mouse peripheral lung of N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and their analogues.

André Castonguay, Dorothy Lin, Gary D. Stoner et al. · PubMed · 1983 · 126 citations

Chemoprevention Strategy, Lung Inflammation, Total Dose +21

Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.

Stephen S. Hecht, Neil Trushin, André Castonguay et al. · PubMed · 1986 · 126 citations

Nasal Mucosa, Epigenetic Change, Dna Methylation +16

Effects of α-deuterium substitution on the mutagenicity of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)¹

Stephen S. Hecht, Dorothy Lin, André Castonguay · Carcinogenesis · 1983 · 99 citations

Methyl Group, Biosynthesis, α-Deuterium Substitution +13

Metabolism of tobacco-specific N-nitrosamines by cultured human tissues.

André Castonguay, Gary D. Stoner, Herman A.J. Schut et al. · Proceedings of the National Academy of Sciences · 1983 · 97 citations · Full text

Nnk Carbonyl Group, Oxidative Stress, Reactive Nitrogen Specie +16