Concepedia

Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat

Xi‐Chun May Lu, Edmond Massuda, Qian Lin, Weixing Li, Jiahe Li, Jie Zhang

Brain Research · 2003 · 66 citations · 15 references

DOI

Concepts

References

15

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

Mikael J. L. Eliasson, Kenji Sampei, Allen S. Mandir et al. · Nature Medicine · 1997 · 1K citations

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Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1

Kevin J. Bitterman, Rozalyn M. Anderson, Haim Cohen et al. · Journal of Biological Chemistry · 2002 · 998 citations · Full text

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Ischemic Brain Injury is Mediated by the Activation of Poly(ADP-Ribose)Polymerase

Matthias Endres, Zhao‐Qi Wang, Shobu Namura et al. · Journal of Cerebral Blood Flow & Metabolism · 1997 · 625 citations

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Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke

Galaleldin E. Abdelkarim, Karen Gertz, Christoph Harms et al. · International Journal of Molecular Medicine · 2001 · 240 citations

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Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

Weihai Ying, Mary B. Sevigny, Yongmei Chen et al. · Proceedings of the National Academy of Sciences · 2001 · 201 citations · Full text

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