Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.8K citations

Education, Genetics, Molecular Biology +12

Directed Differentiation of Embryonic Stem Cells into Motor Neurons

Hynek Wichterle, Ivo Lieberam, Jeffery A. Porter et al. · Cell · 2002 · 1.7K citations · Full text

Life Sciences, Developmental Biology, Neuroscience +16

Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1

Kevin J. Bitterman, Rozalyn M. Anderson, Haim Cohen et al. · Journal of Biological Chemistry · 2002 · 998 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

Tiziano Barberi, Péter Klivènyi, Noel Y. Calingasan et al. · Nature Biotechnology · 2003 · 618 citations

Life Sciences, Neurobiology, Neuroscience +16

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

Timour Prozorovski, Ulf Schulze‐Topphoff, Robert Glumm et al. · Nature Cell Biology · 2008 · 456 citations

Life Sciences, Molecular Biology, Neuroscience +14