Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect

BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Martin Steegmaier, Matthias Hoffmann, Anke Baum et al. · Current Biology · 2007 · 849 citations · Full text

Medicine, Oncology, Pharmacology +14

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic

Ariel Fernández, Ángela Sanguino, Zhenghong Peng et al. · Journal of Clinical Investigation · 2007 · 161 citations · Full text

Medicine, Oncology, Pharmacology +13

Lyn Kinase Activity Is the Predominant Cellular Src Kinase Activity in Glioblastoma Tumor Cells

Michelle R. Stettner, Wenquan Wang, Burt Nabors et al. · Cancer Research · 2005 · 110 citations

Medicine, Cell Biology, Oncology +17

Small Molecule Recognition of c-Src via the Imatinib-Binding Conformation

Arvin C. Dar, Michael S. Lopez, Kevan M. Shokat · Chemistry & Biology · 2008 · 88 citations

Life Sciences, Biochemistry, Molecular Biology +14

Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Expression in Squamous Cell Carcinomas of the Head and Neck

Csilla Neuchrist, Boban M. Erović, Alessandra Handisurya et al. · The Laryngoscope · 2001 · 65 citations

Medicine, Oncology, Pathology +16