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Publication | Open Access

Enhancement of Myocardial Regeneration Through Genetic Engineering of Cardiac Progenitor Cells Expressing Pim-1 Kinase

DOIFull Paper Access

206

Citations

40

References

2009

Year

Kimberlee M. Fischer, Christopher T. Cottage, Weitao Wu, Shabana Din, Natalie Gude, Daniele Avitabile, Pearl Quijada, Brett Collins, Jenna Fransioli, Mark A. Sussman
Circulation

Abstract

Myocardial repair is significantly enhanced by genetic engineering of CPCs with Pim-1 kinase. Ex vivo gene delivery to enhance cellular survival, proliferation, and regeneration may overcome current limitations of stem cell-based therapeutic approaches.

References

YearCitations

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