Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line

Biochemistry and molecular cell biology of diabetic complications

Michael Brownlee · Nature · 2001 · 9K citations

Life Sciences, Biochemistry, Cell Biology +14

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

Paul E. Lacy, Mery Kostianovsky · Diabetes · 1967 · 2.8K citations

Life Sciences, Biochemistry, Physiology +14

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Hideaki Kamata, Shinichi Honda, Shin Maeda et al. · Cell · 2005 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells.

Toyoshi Inoguchi, Pan Li, F. Umeda et al. · Diabetes · 2000 · 1.6K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Fatty acid-induced β cell apoptosis: A link between obesity and diabetes

Michio Shimabukuro, Yan-Ting Zhou, Moshe Levi et al. · Proceedings of the National Academy of Sciences · 1998 · 1.1K citations · Full text

Life Sciences, Cell Biology, Endocrinology +17