Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

Yujiang Geno Shi, Yujiang Geno Shi, Fei Lan et al. · Cell · 2004 · 4K citations · Full text

Life Sciences, Genetics, Molecular Biology +11

p53 is regulated by the lysine demethylase LSD1

Jing Huang, Roopsha Sengupta, Alexsandra Espejo et al. · Nature · 2007 · 798 citations

Life Sciences, Genetics, Molecular Biology +10

Snail and Slug Promote Epithelial-Mesenchymal Transition through β-Catenin–T-Cell Factor-4-dependent Expression of Transforming Growth Factor-β3

Damian Medici, Elizabeth D. Hay, Bjørn R. Olsen · Molecular Biology of the Cell · 2008 · 492 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

Shinya Hayami, John D. Kelly, Hyun‐Soo Cho et al. · International Journal of Cancer · 2010 · 481 citations · Full text

Medicine, Molecular Biology, Oncology +16

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

Soyoung Lim, Andreas Janzer, Astrid Becker et al. · Carcinogenesis · 2009 · 464 citations

Medicine, Molecular Biology, Oncology +16