Andreas Janzer

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

David B. Sykes, Youmna Kfoury, François Mercier et al. · Cell · 2016 · 488 citations · Full text

Medicine, Oncology, Pharmacology +14

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

Soyoung Lim, Andreas Janzer, Astrid Becker et al. · Carcinogenesis · 2009 · 464 citations

Medicine, Molecular Biology, Oncology +16

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

Andreas Janzer, Natalie J. German, Karina N. Gonzalez-Herrera et al. · Proceedings of the National Academy of Sciences · 2014 · 262 citations · Full text

Life Sciences, Oncology, Pharmacology +17

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies

Sven Christian, Claudia Merz, Laura Evans et al. · Leukemia · 2019 · 246 citations · Full text

Medicine, Hematology, Pharmacology +17

Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation

Asaf Rotem, Andreas Janzer, Benjamin Izar et al. · Proceedings of the National Academy of Sciences · 2015 · 138 citations · Full text

Medicine, Cancer Biology, Oncology +14