Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-κB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis

Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Per‐Johan Jakobsson, Staffan Thorén, Ralf Morgenstern et al. · Proceedings of the National Academy of Sciences · 1999 · 995 citations

Life Sciences, Molecular Biology, Pharmacology +14

Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.

P. Charles, M. J. Elliott, Diana Davis et al. · PubMed · 1999 · 533 citations

Life Sciences, Immunology, Internal Medicine +17

Regulation of Cytokines, Cytokine Inhibitors, and Acute-Phase Proteins Following Anti-TNF-α Therapy in Rheumatoid Arthritis

P. Charles, Michael J. Elliott, Diana Davis et al. · The Journal of Immunology · 1999 · 434 citations

Life Sciences, Immunology, Internal Medicine +17

Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade

Marina Lasa, Kamal R Mahtani, Andrew J. Finch et al. · Molecular and Cellular Biology · 2000 · 411 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts.

Richard Bucala, Christopher T. Ritchlin, Robert Winchester et al. · The Journal of Experimental Medicine · 1991 · 267 citations · Full text

Medicine, Immunology, Pathology +15