Concepedia

Liquid chromatographic–mass spectrometric determination of the metabolism and disposition of the anti-retroviral nucleoside analogs zidovudine and lamivudine in C57BL/6N and B6C3F1 mice

Lonnie D. Williams, Linda S. VonTungeln, Frederick A. Beland, Daniel R. Doerge

Journal of Chromatography B · 2003 · 22 citations · 9 references

DOI

Concepts

References

9

Transplacental Effects of 3'-Azido-2',3'-Dideoxythymidine (AZT): Tumorigenicity in Mice and Genotoxicity in Mice and Monkeys

Ofelia A. Olivero, Stuart H. Yuspa, Miriam C. Poirier et al. · JNCI Journal of the National Cancer Institute · 1997 · 227 citations · Full text

, , +16

Differential Incorporation and Removal of Antiviral Deoxynucleotides by Human DNA Polymerase γ

Susan E. Lim, William C. Copeland · Journal of Biological Chemistry · 2001 · 227 citations · Full text

, , +15

Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.

E M Cretton, Mengyu Xie, Ruth Bevan et al. · Molecular Pharmacology · 1991 · 106 citations

, , +7

Multiorgan Transplacental and Neonatal Carcinogenicity of 3′-Azido-3′-deoxythymidine in Mice

Bhalchandra A. Diwan, Charles W. Riggs, Daniel Logsdon et al. · Toxicology and Applied Pharmacology · 1999 · 70 citations

, , +14

Metabolism of 3′-azido-3′-deoxythymidine (AZT) in human placentae trophoblasts and Hofbauer cells

Mingxin Qian, Tot Bui, Rodney J. Y. Ho et al. · Biochemical Pharmacology · 1994 · 46 citations

, , +7