Concepedia

E M Cretton

EM

Statistics

Publications

10

Citations

427

H-Index

10

Active since

1990

Affiliations

University of Alabama at Birmingham(Current)

E M Cretton is an author at University of Alabama at Birmingham specializing in metabolism, biochemistry, and drug metabolism.

Publications per year

1990–1995

10

Publications

10

Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.

E M Cretton, Mengyu Xie, Ruth Bevan et al. · Molecular Pharmacology · 1991 · 106 citations

, , +7

Clinical pharmacokinetics of 3′-azido-3′-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3′-amino-3′-deoxythymidine

M. Patrick Stagg, E M Cretton, Lauren B. Kidd et al. · Clinical Pharmacology & Therapeutics · 1992 · 93 citations

, , +6

Pharmacokinetics of 3'-azido-3'-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys

E M Cretton, Raymond F. Schinazi, Harold M. McClure et al. · Antimicrobial Agents and Chemotherapy · 1991 · 52 citations · Full text

, , +12

In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine

E M Cretton, Z Zhou, Lauren B. Kidd et al. · Antimicrobial Agents and Chemotherapy · 1993 · 40 citations

, , +6

Reduction of 3′-azido-3′-deoxythymidine to 3′-amino-3′-deoxythymidine in human liver microsomes and its relationship to cytochrome P450

L Placidi, E M Cretton, M. Placidi et al. · Clinical Pharmacology & Therapeutics · 1993 · 32 citations

, , +17

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