Vial Freeze-Drying, part 1: New Insights into Heat Transfer Characteristics of Tubing and Molded Vials

Mass and Heat Transfer in Vial Freeze-Drying of Pharmaceuticals: Role of the Vial

Michael J. Pikal, Michael L. Roy, Saroj Shah · Journal of Pharmaceutical Sciences · 1984 · 343 citations

Pharmacy, Food Science, Pharmaceutics +14

Use of laboratory data in freeze drying process design: heat and mass transfer coefficients and the computer simulation of freeze drying.

Pikal Mj · PubMed · 1985 · 200 citations

Agriculture, Food Science, Mechanical Engineering +17

Physical Chemistry of Freeze-drying: Measurement of Sublimation Rates for Frozen Aqueous Solutions by a Microbalance Technique

Michael J. Pikal, Saroj Shah, David E. Senior et al. · Journal of Pharmaceutical Sciences · 1983 · 195 citations

Pharmacy, Biochemistry, Chemistry +10

Heat and mass transfer scale-up issues during freeze-drying, I: Atypical radiation and the edge vial effect

Shailaja Rambhatla, Michael J. Pikal · AAPS PharmSciTech · 2003 · 184 citations · Full text

Pharmacy, Chemical Engineering, Food Science +16

Evaluation of manometric temperature measurement as a method of monitoring product temperature during lyophilization.

Nathaniel Milton, Michael J. Pikal, Michael L. Roy et al. · PubMed · 1997 · 155 citations

Pharmacy, Food Science, Food Analysis +16