Journal of the Chemical Society Chemical Communications · 1972 · 15 citations · 0 references
Natural SciencesChemistryOrganic ChemistryFunctional Group SubstitutionSubstituent EffectsSubstitution ReactionsElectrophilic Aromatic SubstitutionElectrophilic Substitution In HeterocyclesIndole ChemistryIndole DerivativesRegioselectivity In Substitution ReactionsSubstitution MechanismsSubstitution Reactions In Heterocycles
The relative reactivities of a number of indole derivatives in the Vilsmeier–Haack formylation have been determined by a competitive procedure; the data are discussed in terms of possible substitution mechanisms.