Concepedia

Steroidal inhibitors as chemical probes of the active site of aromatase

Robert W. Brueggemeier, Patrick P. Moh, Soheila Ebrahimian, Michael V. Darby

The Journal of Steroid Biochemistry and Molecular Biology · 1993 · 18 citations · 14 references

DOI

Concepts

References

14

Studies on the Mechanism of Estrogen Biosynthesis. VIII. The Development of Inhibitors of the Enzyme System in Human Placenta1

William C. Schwarzel, W. G. KRUGGEL, Harry J. Brodie · Endocrinology · 1973 · 301 citations

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Inactivation of aromatase in vitro by 4-hydroxy-4-androstene-3,17-dione and 4-acetoxy-4-androstene-3,17-dione and sustained effects in vivo

Angela Brodie, Wesley M. Garrett, James R. Hendrickson et al. · Steroids · 1981 · 215 citations

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Bromopyruvate Inactivation of 2-Keto-3-deoxy-6-phosphogluconic Aldolase. I. Kinetic Evidence for Active Site Specificity<sup>*</sup>

H. Paul Meloche · Biochemistry · 1967 · 203 citations

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Synthesis and biochemical evaluation of inhibitors of estrogen biosynthesis

Robert W. Brueggemeier, Eugenia Floyd, Raymond E. Counsell · Journal of Medicinal Chemistry · 1978 · 112 citations · Full text

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ENZYME-GENERATED INTERMEDIATES DERIVED FROM 4-ANDR0STENE-3,6,17-TRI0NE AND 1,4,6-ANDR0STATRIENE-3,17-DI0NE CAUSE A TIME-DEPENDENT DECREASE IN HUMAN PLACENTAL AROMATASE ACTIVITY

Douglas F. Covey, William F. Hood · Endocrinology · 1981 · 104 citations

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