Concepedia

Presence of soluble amyloid β–peptide precedes amyloid plaque formation in Down's syndrome

Jan K. Teller, Claudio Russo, Laura M. DeBusk, Giovanna Angelini, D Zaccheo, Francesca Dagna-Bricarelli, Pietro Scartezzini, Stefano Bertolini, D. M. A. Mann, Massimo Tabaton,

Nature Medicine · 1996 · 327 citations · 17 references

Concepts

Life SciencesBiochemistryNeurologyMolecular PathologyNeurodegenerationNeuropathologyAmyloid FormationDown SyndromeNeurodegenerative DiseasesNeurodegenerative DisordersProtein AggregationProtein MisfoldingAmyloid Beta PeptidesAmyloid Plaque FormationAmyloid Plaques

References

17

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.9K citations

Life Sciences, Biochemistry, Molecular Biology +12

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

Hermann Schägger, Gebhard von Jagow · Analytical Biochemistry · 1987 · 11.5K citations

Life Sciences, Biochemistry, Molecular Biology +10

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

Life Sciences, Molecular Biology, Neurology +16

An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp <sub>717</sub> ) Mutants

Nobuhiro Suzuki, Tobun T. Cheung, Xiao-Dan Cai et al. · Science · 1994 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +16