Concepedia

High expression of heat shock protein 90 alpha and its significance in human acute leukemia cells

Wenliang Tian, Fei He, Xue Fu, Juntang Lin, Ping Tang, Yumin Huang, Rong Guo, Ling Sun

Gene · 2014 · 41 citations · 27 references

DOI

Concepts

References

27

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

, , +9

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

Adeela Kamal, Lia Thao, John Sensintaffar et al. · Nature · 2003 · 1.4K citations

, , +10

Requirement of Hsp90 activity for IκB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κB activation

Meike Broemer, Daniel Krappmann, Claus Scheidereit · Oncogene · 2004 · 219 citations

, , +11

Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Advanced Cancer

David B. Solit, S. Percy Ivy, Catherine Kopil et al. · Clinical Cancer Research · 2007 · 212 citations

, , +17

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

Yutaka Okawa, Teru Hideshima, Paul M. Steed et al. · Blood · 2008 · 209 citations · Full text

, , +16