Concepedia

KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity

Vito Vetrugno, Alessio Cardinale, Ilaria Filesi, Sonia Mattei, Man‐Sun Sy, Maurizio Pocchiari, Silvia Biocca

Biochemical and Biophysical Research Communications · 2005 · 46 citations · 26 references

DOI

Concepts

References

26

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

LA Greene, Arthur S. Tischler · Proceedings of the National Academy of Sciences · 1976 · 5.6K citations · Full text

, , +17

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

, , +17

Separation and properties of cellular and scrapie prion proteins.

R. Meyer, Michael P. McKinley, K A Bowman et al. · Proceedings of the National Academy of Sciences · 1986 · 621 citations · Full text

, , +16

Transmission of the BSE Agent to Mice in the Absence of Detectable Abnormal Prion Protein

Corinne Ida Lasmézas, Jean‐Philippe Deslys, O. Robain et al. · Science · 1997 · 580 citations

, , +16

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

David Peretz, R. Anthony Williamson, Kiotoshi Kaneko et al. · Nature · 2001 · 524 citations

, , +11