Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect

Synthesis and Angiotensin II Receptor Antagonistic Activities of Benzimidazole Derivatives Bearing Acidic Heterocycles as Novel Tetrazole Bioisosteres

Yasuhisa Kohara, Keiji Kubo, Eiko Imamiya et al. · Journal of Medicinal Chemistry · 1996 · 272 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Effects of the Angiotensin Receptor Blocker Azilsartan Medoxomil Versus Olmesartan and Valsartan on Ambulatory and Clinic Blood Pressure in Patients With Stages 1 and 2 Hypertension

William B. White, Michael A. Weber, Domenic Sica et al. · Hypertension · 2011 · 215 citations

Medicine, Pharmacology, Pharmacotherapy +17

The Comparative Effects of Azilsartan Medoxomil and Olmesartan on Ambulatory and Clinic Blood Pressure

George L. Bakris, Domenic Sica, Michael A. Weber et al. · Journal of Clinical Hypertension · 2011 · 141 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series

Peter Bühlmayer, Pascual Furet, Leoluca Criscione et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 106 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

AT₁receptor antagonism attenuates target organ effects of salt excess in SHRs without affecting pressure

Jasmina Varagić, Edward D. Fröhlich, Dinko Sušić et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2007 · 89 citations

Medicine, Cardiology, Pharmacology +17