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Hepatic reticuloendothelial system cell iron deposition is associated with increased apoptosis in nonalcoholic fatty liver disease

Bryan D. Maliken, James E. Nelson, Heather Klintworth, Mary Beauchamp, Matthew M. Yeh, Kris V. Kowdley

Hepatology · 2013 · 83 citations · 34 references

DOIFull text

Open access

Abstract

Presence of iron in liver RES cells is associated with NASH, increased apoptosis, and increased OS. HC iron deposition in NAFLD is also associated with OS and may promote hepatocyte necrosis in this disease.

References

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