Hepatotoxicity studies of sub-chronic administration of aqueous stem bark of khaya senegalensis in albino rats

Abstract

The effect of oral daily administration for twenty eight (28) days of stem bark aqueous extract of Khaya senegalensis on alkaline phosphatase (ALP), aspartate aminotranferase (AST), alanine aminotransferase (ALT) activities and on the level of serum total bilirubin and total protein were investigated using Albino rats in three dose levels (10, 20, and 40 mg/kg body weight) plus a group serving as control. The result obtained indicated significant (p