Concepedia

Fragile sites are preferential targets for integrations of MLV vectors in gene therapy

Assaf C. Bester, Michal Schwartz, Manfred Schmidt, Alexandrine Garrigue, S. Hacein-Bey-Abina, Marina Cavazzana, N Ben-Porat, Christof von Kalle, Alain Fischer, Batsheva Kerem

Gene Therapy · 2006 · 51 citations · 11 references

DOI

Concepts

References

11

<i>LMO2</i> -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

S. Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt et al. · Science · 2003 · 3.6K citations

, , +17

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

, , +17

Transcription Start Regions in the Human Genome Are Favored Targets for MLV Integration

Xiaolin Wu, Yuan Li, Bruce Crise et al. · Science · 2003 · 1.3K citations

, , +17

Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

Rick Mitchell, Brett Beitzel, A. R. W. Schröder et al. · PLoS Biology · 2004 · 978 citations · Full text

, , +15

DNA polymerase ? inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

Thomas W. Glover, Carol Berger, Jane Coyle et al. · Human Genetics · 1984 · 598 citations

, , +17