Similarities in the Biodistribution of Iodine-Labeled Anti-Tac Single-Chain Disulfide-Stabilized Fv Fragment and Anti-Tac Disulfide-Stabilized Fv Fragment

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications · 1978 · 4.6K citations

Life Sciences, Biochemistry, Cell Biology +8

Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms.

Takashi Yokota, Diane E. Milenic, Marc Whitlow et al. · PubMed · 1992 · 826 citations

Pharmacy, Oncology, Pharmacokinetics +17

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells, and on one of two types of helper T cells.

T. Uchiyama, David L. Nelson, T.A. Fleisher et al. · The Journal of Immunology · 1981 · 348 citations

Life Sciences, Cell Biology, Immunology +15

In Vivo Tumor Targeting of a Recombinant Single-Chain Antigen-Binding Protein

David Colcher, Robert E. Bird, Mario Roselli et al. · JNCI Journal of the National Cancer Institute · 1990 · 303 citations

Pharmacy, Molecular Biology, Oncology +17

[3] Protein engineering of single-chain Fv analogs and fusion proteins

James S. Huston, M Mudgett-Hunter, Mei-Sheng Tai et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1991 · 211 citations

Life Sciences, Biochemistry, Bioengineering +13