The in vivo effects of the Pro12Ala PPARγ2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

Samir S. Deeb, Lluís Fajas, Masami Nemoto et al. · Nature Genetics · 1998 · 1.3K citations · Full text

Medicine, Endocrinology, Pharmacology +17

Tissue Distribution and Quantification of the Expression of mRNAs of Peroxisome Proliferator–Activated Receptors and Liver X Receptor-α in Humans: No Alteration in Adipose Tissue of Obese and NIDDM Patients

Didier Auboeuf, Jennifer Rieusset, Lluís Fajas et al. · Diabetes · 1997 · 693 citations

Life Sciences, Biochemistry, Molecular Biology +17

Molecular Scanning of the Human Peroxisome Proliferator Activated Receptor γ (hPPARγ) Gene in Diabetic Caucasians: Identification of a Pro12Ala PPARγ2 Missense Mutation

Chung‐Jen Yen, Brock A. Beamer, Carlo Negri et al. · Biochemical and Biophysical Research Communications · 1997 · 492 citations · Full text

Medicine, Genetics, Molecular Genetics +16

A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM

Giuseppe Paolisso, P. Antonio Tataranni, James E. Foley et al. · Diabetologia · 1995 · 352 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +10

Blood Flow through Human Adipose Tissue Determined with Radioactive Xenon

O. Andrée Larsen, Niels A. Lassen, F Quaade · Acta Physiologica Scandinavica · 1966 · 337 citations

Agriculture, Nutrition, Physiology +11